The Hidden Connection Between Human Papillomavirus (HPV) infection and Male Infertility: What Every Man Needs to Know

Posted on March 04, 2025 by Justin Houman

HPV and Male Fertility: A Silent Threat

When most people think about human papillomavirus (HPV), they associate it with cervical cancer in women. However, recent research suggests that HPV may also pose a significant threat to male fertility—a topic that often goes overlooked. As a men’s health urologist and testosterone doctor, I frequently encounter men struggling with male infertility in Los Angeles and Beverly Hills, and one emerging concern is how sexually transmitted infections (STIs) like HPV may impact sperm health and overall reproductive function.

Understanding HPV and Its Impact on Sperm Health

HPV is the most common STI worldwide, with millions of new cases reported each year. While many strains of HPV cause no symptoms, some high-risk types are linked to cancer, and even low-risk types can lead to genital warts. But what does this mean for male infertility?

Studies show that HPV can negatively affect sperm in multiple ways:

  • DNA Fragmentation: HPV-infected sperm exhibit higher rates of DNA fragmentation, which reduces fertilization potential and increases miscarriage risks.
  • Reduced Motility: Sperm infected with HPV often show decreased motility, making it harder for them to reach and fertilize an egg.
  • Abnormal Morphology: Structural changes in sperm caused by HPV may hinder conception.
  • Higher Risk of Miscarriage: If fertilization does occur, the presence of HPV in sperm has been linked to an increased likelihood of miscarriage due to genetic instability.

How HPV Affects Male Hormones and Testosterone Levels

Although HPV primarily affects reproductive health, there is growing interest in its potential link to hormonal balance. As a testosterone doctor in Beverly Hills, I frequently assess men for hormonal imbalances that could be influencing their fertility. Some studies suggest that chronic infections like HPV may contribute to systemic inflammation, which could interfere with testosterone production. Low testosterone can further exacerbate fertility issues by reducing sperm count and motility.

Can You Test for HPV in Men?

Unlike women, who undergo routine HPV screening through Pap smears, there is no standard test for HPV in men. However, specialized testing can detect HPV in semen or urethral swabs, particularly in cases where infertility is unexplained.

Treatment and Prevention: Protecting Your Fertility

If you’re concerned about HPV and its impact on your fertility, here’s what you can do:

  • Get the HPV Vaccine: The Gardasil 9 vaccine protects against the most harmful HPV strains and is FDA-approved for men up to age 45.
  • Use Protection: While condoms don’t offer 100% protection against HPV, they significantly reduce transmission risk.
  • Optimize Your Sperm Health: A balanced diet, regular exercise, and testosterone optimization therapy (when medically appropriate) can support fertility and overall men’s health.
  • See a Men’s Health Urologist: If you’re experiencing fertility struggles, consulting with a male infertility specialist in Los Angeles or Beverly Hills can help determine if HPV or other factors are at play.

Final Thoughts

HPV is not just a concern for women—it’s a major issue for men, too, particularly when it comes to male infertility. If you and your partner are struggling to conceive, it’s essential to explore all possible causes, including HPV. As a leading men’s health urologist and testosterone doctor, I can help assess and optimize your reproductive health.

Need Expert Guidance on Male Infertility?

If you’re looking for a male infertility specialist in Los Angeles or Beverly Hills, or want to learn more about testosterone and reproductive health, schedule a consultation with Dr. Justin Houman today. Your fertility matters, and the right expert care can make all the difference.

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